Longitudinal relationship certainly one of coronary artery calcification, solution phosphorus, and you may kidney form


Longitudinal relationship certainly one of coronary artery calcification, solution phosphorus, and you may kidney form

18. O’Seaghdha CM, Hwang SJ, Muntner P, Melamed ML, Fox CS. Solution phosphorus forecasts experience chronic kidney condition and avoid-stage kidney problem. Nephrol Switch Transplant. 2011;26(9):2885-2890. (PubMed)

19. Foley Registered nurse, Collins AJ, Herzog California, Ishani A beneficial, Kalra PA. Serum phosphate and you will left ventricular hypertrophy when you look at the young adults: new coronary artery exposure growth in young people analysis. Renal Bloodstream Drive Res. 2009;32(1):37-44. (PubMed)

20. Shuto E, Taketani Y, Tanaka Roentgen, ainsi que al. Diet phosphorus excessively impairs endothelial form. J Was Soc Nephrol. 2009;20(7):1504-1512. (PubMed)

twenty-two. de- Boer IH, Rue TC, Kestenbaum B. Solution phosphorus concentrations throughout the third National Health insurance and Diet Examination Questionnaire (NHANES III). Am J Kidney Dis. 2009;53(3):399-407. (PubMed)

23. Isakova T, Wahl P, Vargas GS, ainsi que al. Fibroblast growth grounds 23 try raised in advance of parathyroid hormones and phosphate into the persistent kidney situation. Kidney Int. 2011;79(12):1370-1378. (PubMed)

twenty-four. Isakova T, Xie H, Yang W, mais aussi al. Fibroblast development factor 23 and you can risks of death and you will stop-phase kidney disease into the customers that have persistent renal problem. JAMA. 2011;305(23):2432-2439. (PubMed)

twenty-five. Palmer South carolina, Hayen A, Macaskill P, ainsi que al. Gel quantities of phosphorus, parathyroid hormone, and you can calcium supplements and you may risks of demise and you can cardiovascular disease for the some one having persistent kidney situation: a logical opinion and you may meta-research. JAMA. 2011;305(11):1119-1127. (PubMed)

27. Hruska KA, Mathew S, Lund R, Qiu P, Pratt Roentgen. Hyperphosphatemia off chronic renal problem. Kidney Int. 2008;74(2):148-157. (PubMed)

twenty-eight. Jono S, McKee MD, Murry Le, mais aussi al. Phosphate control of vascular smooth muscle tissue telephone calcification. Circ Res. 2000;87(7):E10-17. (PubMed)

29. Rennenberg RJ, Kessels AG, Schurgers LJ, van Engelshoven JM, de- Leeuw PW, Kroon AA. Vascular calcifications as a beneficial marker regarding increased aerobic exposure: an excellent meta-data. Vasc Health Risk Manag. 2009;5(1):185-197. (PubMed)

29. Chang AR, Lazo Meters, Appel LJ, Gutierrez OM, Grams Me. Highest losing weight phosphorus intake was of all-cause death: comes from NHANES III. Am J Clin Nutr. 2014;99(2):320-327. (PubMed)

31. Calvo MS, Playground YK. Modifying phosphorus content of one’s You diet plan: possibility adverse effects toward limbs. J Nutr. 1996;126(4 Suppl):1168S-1180S. (PubMed)

33. Kemi VE, Karkkainen MU, Rita HJ, Laaksonen MM, Outila TA, Lamberg-Allardt CJ. Lower calcium:phosphorus ratio from inside the habitual diets influences solution parathyroid hormone amount and you may calcium metabolism within the match girls having enough calcium supplements consumption. Br J Nutr. 2010;103(4):561-568. (PubMed)

34. Grimm Yards, Muller A, Hein Grams, Funfstuck R, Jahreis Grams. Highest phosphorus consumption just slightly has an effect on serum nutrients, urinary pyridinium crosslinks and you will kidney mode within the women. Eur J Clin Nutr. 2001;55(3):153-161. (PubMed)

35. Pinheiro MM, Schuch Nj, Genaro PS, Ciconelli RM, Ferraz MB, Martini La. Mineral intakes related to osteoporotic cracks within the men and women–the fresh Brazilian Osteoporosis Investigation (BRAZOS). Nutr J. 2009;8:6. (PubMed)

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Ramifications of intercourse and you can postmenopausal estrogen explore into gel phosphorus levels: a corner-sectional examination of the newest National Health and Nourishment Test Survey (NHANES) 2003-2006

thirty six. Calvo MS, Tucker KL. Was phosphorus intake one to exceeds weight-loss standards a danger cause for limbs wellness? Ann Letter Y Acad Sci. 2013; -thirty five. (PubMed)

38. Cervelli MJ, Shaman A, Meade A, Carroll Roentgen, McDonald SP. Effectation of stomach acid inhibition having pantoprazole to the efficacy of calcium carbonate once the a beneficial phosphate binder for the haemodialysis customers. Nephrology (Carlton). 2012;17(5):458-465. (PubMed)

40. Bansal N, Katz Roentgen, de Boer IH, ainsi que al. Determine away from estrogen treatment into calcium, phosphorus, or other regulatory hormonal for the postmenopausal people: the newest MESA study. J Clin Endocrinol Metab. 2013;98(12):4890-4898. (PubMed)

Supplies

Phosphorus homeostasis try securely managed by the PTH/vitamin D/FGF-23 axis into the individuals with regular renal setting (pick Regulation). Enhanced secretion regarding PTH and you will FGF-23 helps maintain phosphorus solution levels throughout the regular diversity (dos.5-cuatro.5 mg/dL) even yet in the setting regarding higher phosphorus consumption (9). Which leads to serum phosphorus being only weakly coordinated to phosphorus use (22). Out-of mention, suffered grows for the FGF-23 and PTH are generally noticed while in the CKD to take care of regular gel phosphorus levels even after a decrease in urinary phosphorus excretion (23). Raised FGF-23, in lieu of gel phosphorus, is apparently an early marker away from disordered phosphorus homeostasis and you will a good predictor away from adverse wellness consequences in patients with very early-phase CKD (23, 24). Hence, it’s realistic to assume one to measuring solution phosphorus in the anyone that have regular kidney setting you should never acceptably mirror very early interruptions inside the phosphorus metabolism due to highest phosphorus consumption.

A mix-sectional research used in two,344 Brazilian group (average age, 58 many years) demonstrated an association ranging from highest phosphorus intakes and you may enhanced risk of fracture. Yet, consumption regarding most other vitamins and minerals relevant to limbs health, particularly calcium, magnesium, and you may supplement D, have been underneath the RDA contained in this people, while phosphorus consumption was near the RDA (35). While it appears that hormone and you will calcium supplements conditions could be averted by an acceptable calcium-to-phosphorus intake ratio, there is absolutely no persuading facts your fat loss phosphorus accounts knowledgeable in the usa negatively connect with bone mineral occurrence. Still, the latest replacement off phosphate-containing carbonated drinks and you will goodies to possess whole milk or any other calcium-steeped dining could possibly get represent a significant exposure so you can bone health (comprehend the overview of Calcium) (36).

17. Tonelli Meters, Sacks F, Pfeffer M, mais aussi al. Relation ranging from solution phosphate height and you may cardiovascular event price in the people that have coronary disease. Circulation. 2005;112(17):2627-2633. (PubMed)